First, regardless of perceptions of U.S. complicity in the attack, the United States would probably become embroiled militarily in any Iranian retaliation against Israel or other countries in the region. Given uncertainties about the future of Iraq and a deepening commitment to Afghanistan, hostilities with Iran would stretch U.S. military capabilities at a particularly difficult time while potentially derailing domestic priorities.
Second, an Israeli strike would cause oil prices to spike and heighten concerns that energy supplies through the Persian Gulf may become disrupted.