June 2, 2004

Esmail D. Zanjani found that a few cells in sheep go on using an injected marker gene for years. Gene therapy with fetuses has been tested-with mixed results-in sheep, monkeys, and mice. Dr. Zanjani, a professor of medicine and physiology at the University of Nevada's medical school at Reno and a collaborator of Dr. Anderson's, has injected sheep fetuses with a new marker gene and found that some of the animals continue to use the gene for years to make a protein. But the proportion of cells that do so is low, he reported >>> See

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