Afghanistan's president has criticised US forces for "unilateral operations" in the west which, the government says, killed at least 70 civilians.
A spokesman for the US task force, that operates outside Nato, said an inquiry was under way. The US had initially denied any civilians had died.
Meanwhile, police say 10 civilians have been killed by a roadside bomb in the south of the country.
The victims were travelling in a minibus between Kabul and Kandahar.
Correspondents say roadside bombs in Afghanistan usually set to target security forces, but are often triggered early and kill civilians.
Protest death
The US operations in the west of the country have led to renewed tensions between President Hamid Karzai and the international forces. Tribal elders said a bomb had been dropped on a large group of mourners at a wake in Herat on Friday.
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