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WASHINGTON — The United States and Israel on Monday said Iran is among the "greatest challenges" to stability in the Middle East and reaffirmed their commitment to preventing the country from developing nuclear weapons.

After talks in Washington, senior U.S. and Israeli officials said in a joint statement that Iran's nuclear program, along with its support of anti-Israel militant groups, are of "grave concern," and they pledged to keep Iran from acquiring atomic arms. The discussions were part of the semiannual U.S.-Israel Strategic Dialogue.

"While today's strategic dialogue covered many subjects, it is clear that Iran is among the greatest challenges we face today in the Middle East," said the statement, which was released by the State Department in the names of Deputy Secretary of State James Steinberg and Israeli Deputy Foreign Minister Daniel Ayalon.