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U.N. nuclear agency chief Yukiya Amano complained on Thursday about Iran's lack of cooperation with his inspectors, four days before long-stalled talks resume between Tehran and major powers.

Amano's comments to the 35-nation governing board of the International Atomic Energy Agency (IAEA) highlight the challenges that negotiators will face in seeking to resolve a dispute over the Islamic state's nuclear ambitions.

"The agency needs  Iran's cooperation in clarifying outstanding issues which give rise to concerns about possible military dimensions to its nuclear program, including by providing access to all sites, equipment, persons and documents requested by the agency," Amano said in a speech.