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House and Senate negotiators reached agreement late Monday on legislation that builds on the current penalties directed at financial institutions that do business with Iran’s central bank. The new bill would impose sanctions on anyone who mines uranium with Iran; sells, leases or provides oil tankers to Tehran; or provides insurance to the National Iranian Tanker Co., the state-run shipping line.

Unless Iranians ‘‘come clean on their nuclear program, end the suppression of their people and stop supporting terrorist activities, they will face deepening international isolation and even greater economic and diplomatic pressure,’’ said Sen. Tim Johnson, D-S.D., chairman of the Senate Banking Committee.